Z-PRO-VAL-OH
Contact usFactory supply good quality Z-PRO-VAL-OH 21285-27-8 with stock
- Molecular Formula: C18H24 N2 O5
- Molecular Weight: 348.399
- Vapor Pressure: 1.27E-14mmHg at 25°C
- Boiling Point: 587°Cat760mmHg
- Flash Point: 308.8°C
- PSA: 95.94000
- Density: 1.246g/cm3
- LogP: 2.34180
Z-PRO-VAL-OH(Cas 21285-27-8) Usage
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General Description |
Z-PRO-VAL-OH is a chemical compound that belongs to the family of amino acids, specifically a derivative of proline. It is classified as a non-proteinogenic amino acid, meaning it is not commonly found in proteins but has various biological roles. Z-PRO-VAL-OH is known for its ability to act as a building block for peptides and proteins, playing a crucial role in protein synthesis and structural stability. Additionally, this compound has been studied for its potential therapeutic applications, such as its anti-inflammatory properties and ability to regulate immune responses. Overall, Z-PRO-VAL-OH is a versatile and important molecule with promising biomedical uses. |
InChI:InChI=1/C18H24N2O5/c1-12(2)15(17(22)23)19-16(21)14-9-6-10-20(14)18(24)25-11-13-7-4-3-5-8-13/h3-5,7-8,12,14-15H,6,9-11H2,1-2H3,(H,19,21)(H,22,23)
21285-27-8 Relevant articles
Synthesis of dipeptides from N-hydroxy-3-azaspiro[5,5]undecane-2,4-dione activated α-amino acids
Nowshuddin, Shaik,Ram Reddy
scheme or table, p. 22 - 25 (2011/04/18)
A simple two step procedure for the synt...
Synthesis of proline-derived dipeptides and their catalytic enantioselective direct aldol reactions: Catalyst, solvent, additive and temperature effects
Chen,Sung,Sung, Kuangsen
experimental part, p. 839 - 845 (2010/08/06)
A series of dipeptides of l-proline-l-am...
Efficient peptide coupling involving sterically hindered amino acids
Katritzky, Alan R.,Todadze, Ekaterina,Angrish, Parul,Draghici, Bogdan
, p. 5794 - 5801 (2008/02/09)
(Chemical Equation Presented) Hindered a...
An Effective Water-Free Aprotic System for Dissolving Free Amino Acids
Raydnov, M. G.,Klimenko, L. V.,Mitin, Yu. V.
, p. 283 - 287 (2007/10/03)
An effective water-free system was propo...
21285-27-8 Process route
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-
886981-23-3
benzyl (2S)-2-(1H-1,2,3-benzotriazol-1-ylcarbonyl)tetrahydro-1H-pyrrole-1-carboxylate
-
-
72-18-4,25609-85-2,7004-03-7,921-10-8
L-valine
-
-
21285-27-8
(2S)-2-[({(2S)-1-[(benzyloxy)carbonyl]tetrahydro-1H-pyrrol-2-yl}carbonyl)amino]-3-methylbutanoic acid
| Conditions | Yield |
|---|---|
|
With
triethylamine;
In
water; acetonitrile;
at 20 ℃;
for 1h;
|
95%
|
-
-
72-18-4,25609-85-2,7004-03-7,921-10-8
L-valine
-
-
Z-Pro-OBt
-
-
21285-27-8
(2S)-2-[({(2S)-1-[(benzyloxy)carbonyl]tetrahydro-1H-pyrrol-2-yl}carbonyl)amino]-3-methylbutanoic acid
| Conditions | Yield |
|---|---|
|
Z-Pro-OBt;
With
benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride;
In
N,N-dimethyl-formamide;
at 0 ℃;
for 0.5h;
L-valine;
With
sodium perchlorate; triethylamine;
In
N,N-dimethyl-formamide;
at 20 ℃;
for 1h;
|
85%
|
21285-27-8 Upstream products
-
2874-20-6
benzyloxycarbonyl-L-prolin-L-valin methyl ester
-
26061-29-0
(S)-benzyl 2-((S)-1-tert-butoxy-3-methyl-1-oxobutan-2-ylcarbamoyl)pyrrolidine-1-carboxylate
-
99909-22-5
Z-Pro-Val-OBzl
-
72-18-4
L-valine
21285-27-8 Downstream products
-
52899-09-9
N -L-prolyl-L-valine
-
67545-92-0
(S )-2-((S )-4-isopropyl-5-oxo-4,5-dihydro-oxazol-2-yl)-pyrrolidine-1-carboxylic acid benzyl ester
-
51782-86-6
Z-Pro-Val-Pro-OCH3
-
28334-65-8
Z-S-Pro-S-Val-S-Pro-OtBu
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