Z-PRO-VAL-OH

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Factory supply good quality Z-PRO-VAL-OH 21285-27-8 with stock

  • Molecular Formula: C18H24 N2 O5
  • Molecular Weight: 348.399
  • Vapor Pressure: 1.27E-14mmHg at 25°C 
  • Boiling Point: 587°Cat760mmHg 
  • Flash Point: 308.8°C 
  • PSA: 95.94000 
  • Density: 1.246g/cm3 
  • LogP: 2.34180 

Z-PRO-VAL-OH(Cas 21285-27-8) Usage

General Description

Z-PRO-VAL-OH is a chemical compound that belongs to the family of amino acids, specifically a derivative of proline. It is classified as a non-proteinogenic amino acid, meaning it is not commonly found in proteins but has various biological roles. Z-PRO-VAL-OH is known for its ability to act as a building block for peptides and proteins, playing a crucial role in protein synthesis and structural stability. Additionally, this compound has been studied for its potential therapeutic applications, such as its anti-inflammatory properties and ability to regulate immune responses. Overall, Z-PRO-VAL-OH is a versatile and important molecule with promising biomedical uses.

InChI:InChI=1/C18H24N2O5/c1-12(2)15(17(22)23)19-16(21)14-9-6-10-20(14)18(24)25-11-13-7-4-3-5-8-13/h3-5,7-8,12,14-15H,6,9-11H2,1-2H3,(H,19,21)(H,22,23)

21285-27-8 Relevant articles

Synthesis of dipeptides from N-hydroxy-3-azaspiro[5,5]undecane-2,4-dione activated α-amino acids

Nowshuddin, Shaik,Ram Reddy

scheme or table, p. 22 - 25 (2011/04/18)

A simple two step procedure for the synt...

Synthesis of proline-derived dipeptides and their catalytic enantioselective direct aldol reactions: Catalyst, solvent, additive and temperature effects

Chen,Sung,Sung, Kuangsen

experimental part, p. 839 - 845 (2010/08/06)

A series of dipeptides of l-proline-l-am...

Efficient peptide coupling involving sterically hindered amino acids

Katritzky, Alan R.,Todadze, Ekaterina,Angrish, Parul,Draghici, Bogdan

, p. 5794 - 5801 (2008/02/09)

(Chemical Equation Presented) Hindered a...

An Effective Water-Free Aprotic System for Dissolving Free Amino Acids

Raydnov, M. G.,Klimenko, L. V.,Mitin, Yu. V.

, p. 283 - 287 (2007/10/03)

An effective water-free system was propo...

21285-27-8 Process route

benzyl (2S)-2-(1H-1,2,3-benzotriazol-1-ylcarbonyl)tetrahydro-1H-pyrrole-1-carboxylate
886981-23-3

benzyl (2S)-2-(1H-1,2,3-benzotriazol-1-ylcarbonyl)tetrahydro-1H-pyrrole-1-carboxylate

L-valine
72-18-4,25609-85-2,7004-03-7,921-10-8

L-valine

(2S)-2-[({(2S)-1-[(benzyloxy)carbonyl]tetrahydro-1H-pyrrol-2-yl}carbonyl)amino]-3-methylbutanoic acid
21285-27-8

(2S)-2-[({(2S)-1-[(benzyloxy)carbonyl]tetrahydro-1H-pyrrol-2-yl}carbonyl)amino]-3-methylbutanoic acid

Conditions
Conditions Yield
With triethylamine; In water; acetonitrile; at 20 ℃; for 1h;
95%
L-valine
72-18-4,25609-85-2,7004-03-7,921-10-8

L-valine

Z-Pro-OBt

Z-Pro-OBt

(2S)-2-[({(2S)-1-[(benzyloxy)carbonyl]tetrahydro-1H-pyrrol-2-yl}carbonyl)amino]-3-methylbutanoic acid
21285-27-8

(2S)-2-[({(2S)-1-[(benzyloxy)carbonyl]tetrahydro-1H-pyrrol-2-yl}carbonyl)amino]-3-methylbutanoic acid

Conditions
Conditions Yield
Z-Pro-OBt; With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In N,N-dimethyl-formamide; at 0 ℃; for 0.5h;
L-valine; With sodium perchlorate; triethylamine; In N,N-dimethyl-formamide; at 20 ℃; for 1h;
85%

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