(+)-1-(tert-butylamino)-3-[(4-morpholino-1,2,5-thiadiazol-3-yl)oxy]propan-2-ol
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1.What is the (+)-1-(tert-butylamino)-3-[(4-morpholino-1,2,5-thiadiazol-3-yl)oxy]propan-2-ol ?
(R)-Timolol (Timolol EP Impurity A; Timolol BP Impurity A; Timolol USP Related Compound A) is an antihypertensive agent that increases ocular blood flow and reduces intraocular pressure. (R)-Timolol is an β-adrenergic blocking agent that binds only to nonspecific sites in the particulate fraction of the heart, lungs, and brain.
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29023-48-1,47148-57-2
timolol
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26839-75-8,47148-57-2
timolol
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26839-76-9,47148-57-2
R-(+)-1-tert-butylamino-3-[(4-morpholino-1,2,5-thiadiazol-3-yl)oxy]-2-propanol
| Conditions | Yield |
|---|---|
|
With
AmyCoat (150x46 mm, 3 μm size silica particle);
In
ethanol; n-heptane; diethylamine;
at 27 ℃;
Resolution of racemate;
|
-
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30165-97-0
3-hydroxy-4-(N-morpholino)-1,2,5-thiadiazole
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67843-74-7,24969-06-0,13403-37-7
(S)-epichlorohydrin
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75-64-9
tert -butylamine
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26839-76-9,47148-57-2
R-(+)-1-tert-butylamino-3-[(4-morpholino-1,2,5-thiadiazol-3-yl)oxy]-2-propanol
| Conditions | Yield |
|---|---|
|
3-hydroxy-4-(N-morpholino)-1,2,5-thiadiazole; (S)-epichlorohydrin;
With
sodium carbonate;
In
tetrahydrofuran;
at 60 - 65 ℃;
for 14.5h;
tert-butylamine;
at 44 - 46 ℃;
for 3h;
Product distribution / selectivity;
|
98.6 % ee
|
2.What is the CAS number for (+)-1-(tert-butylamino)-3-[(4-morpholino-1,2,5-thiadiazol-3-yl)oxy]propan-2-ol ?
The CAS number of (+)-1-(tert-butylamino)-3-[(4-morpholino-1,2,5-thiadiazol-3-yl)oxy]propan-2-ol is 26839-76-9.
More information of (+)-1-(tert-butylamino)-3-[(4-morpholino-1,2,5-thiadiazol-3-yl)oxy]propan-2-ol 26839-76-9 are:
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CAS?Number |
26839-76-9 |
|
Density |
1.224g/cm3 |
|
Boiling Point |
487.2°Cat760mmHg |
|
Flash Point |
248.5°C |
|
Vapor Pressure |
2.62E-10mmHg at 25°C |
|
Refractive Index |
1.548 |
|
HS CODE |
2934999090 |
|
PSA |
107.98000 |
|
LogP |
0.95840 |
3.What are another words for (+)-1-(tert-butylamino)-3-[(4-morpholino-1,2,5-thiadiazol-3-yl)oxy]propan-2-ol ?
Synonyms?for?(+)-1-(tert-butylamino)-3-[(4-morpholino-1,2,5-thiadiazol-3-yl)oxy]propan-2-ol 26839-76-9:2-Propanol,1-(tert-butylamino)-3-[(4-morpholino-1,2,5-thiadiazol-3-yl)oxy]-, (+)- (8CI);2-Propanol,1-[(1,1-dimethylethyl)amino]-3-[[4-(4-morpholinyl)-1,2,5-thiadiazol-3-yl]oxy]-,(R)-; 1,2,5-Thiadiazole, 2-propanol deriv.; (+)-Timolol; (R)-(+)-Timolol;(R)-Timolol; L 714465; d-Timolol
4.What is the molecular formula of (+)-1-(tert-butylamino)-3-[(4-morpholino-1,2,5-thiadiazol-3-yl)oxy]propan-2-ol?
The chemical formula of ?(+)-1-(tert-butylamino)-3-[(4-morpholino-1,2,5-thiadiazol-3-yl)oxy]propan-2-ol is?C13H24 N4 O3 S which containing 13 Carbon atoms,24 Hydrogen atoms,4 Nitrogen atoms,3 Oxygen atoms and 1 Sulfur atoms,and the molecular weight of??(+)-1-(tert-butylamino)-3-[(4-morpholino-1,2,5-thiadiazol-3-yl)oxy]propan-2-ol?is 316.425.
5.What is (+)-1-(tert-butylamino)-3-[(4-morpholino-1,2,5-thiadiazol-3-yl)oxy]propan-2-ol (26839-76-9) used for?
(+)-1-(tert-butylamino)-3-[(4-morpholino-1,2,5-thiadiazol-3-yl)oxy]propan-2-ol is a complex organic compound characterized by its unique molecular structure. It features a tert-butylamino group, a morpholino-thiadiazol-3-yloxy group, and a propan-2-ol backbone. (+)-1-(tert-butylamino)-3-[(4-morpholino-1,2,5-thiadiazol-3-yl)oxy]propan-2-ol is known for its potential applications in various industries due to its distinct chemical properties.
InChI:InChI=1/C13H24N4O3S/c1-13(2,3)14-8-10(18)9-20-12-11(15-21-16-12)17-4-6-19-7-5-17/h10,14,18H,4-9H2,1-3H3/t10-/m1/s1
Relevant articles related to (+)-1-(tert-butylamino)-3-[(4-morpholino-1,2,5-thiadiazol-3-yl)oxy]propan-2-ol:
|
Article |
Source |
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Chiral separations of some β-adrenergic agonists and antagonists on AmyCoat column by HPLC |
Ali, Imran,Saleem, Kishwar,Gaitonde, Vinay D.,Aboul-Enein, Hassan Y.,Hussain, Iqbal experimental part, p. 24 - 28 (2010/09/14) |
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An improved process of separation of R- and S-timolol |
Varkonyi-Schlovicsko, Erika,Takacs, Kalman,Hermecz, Istvan , p. 1065 - 1066 (2007/10/03) |
6.Buy (+)-1-(tert-butylamino)-3-[(4-morpholino-1,2,5-thiadiazol-3-yl)oxy]propan-2-ol with the best price .
Shanghai Anya Chemicals Co.,Ltd is a quality supplier of (+)-1-(tert-butylamino)-3-[(4-morpholino-1,2,5-thiadiazol-3-yl)oxy]propan-2-ol. Our main goal is customer satisfaction. Contact us to negotiate the best price for your business on (+)-1-(tert-butylamino)-3-[(4-morpholino-1,2,5-thiadiazol-3-yl)oxy]propan-2-ol 26839-76-9.
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