3-Fluoroacetanilide
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1.What is the 3-Fluoroacetanilide ?
3''-Fluoroacetanilide is a reactant in the preparation of trifluoromethylaryl acetamides via Pd-catalyzed trifluoromethylation of aromatics C-H bond with Umemoto''s reagent directed by acetamino group.
-
-
372-19-0
meta-fluoroaniline
-
-
75-05-8,26809-02-9
acetonitrile
-
-
351-28-0
N-(3-fluorophenyl)acetamide
| Conditions | Yield |
|---|---|
|
With
aluminum oxide;
at 200 ℃;
for 0.45h;
under 37503.8 Torr;
Sonication;
Green chemistry;
|
99%
|
|
With
chloro-trimethyl-silane; potassium iodide;
at 110 ℃;
for 0.25h;
Microwave irradiation;
|
76%
|
|
With
tert.-butylnitrite; trifluorormethanesulfonic acid; water;
at 60 ℃;
for 24h;
|
45%
|
-
-
372-19-0
meta-fluoroaniline
-
-
108-24-7
acetic anhydride
-
-
351-28-0
N-(3-fluorophenyl)acetamide
| Conditions | Yield |
|---|---|
|
With
acetic acid;
at 105 ℃;
for 3h;
|
100%
|
|
With
silica-coated ferrite nanoparticles supported with montmorillonite-K10;
at 20 ℃;
for 0.333333h;
|
92%
|
|
With
sodium acetate;
In
water;
at 0 ℃;
for 1h;
Inert atmosphere;
|
87%
|
|
at 0 - 20 ℃;
Inert atmosphere;
|
84%
|
|
at 50 ℃;
for 3h;
|
82%
|
|
at 0 - 70 ℃;
Inert atmosphere;
|
71%
|
|
In
acetic acid;
for 0.333333h;
Heating;
|
70%
|
|
With
acetic acid;
|
70%
|
|
|
|
|
With
benzene;
|
|
|
In
dichloromethane;
at 20 ℃;
Inert atmosphere;
|
|
|
With
sodium dodecyl sulfate;
In
water;
at 20 ℃;
for 0.5h;
|
|
|
In
dichloromethane;
at 20 ℃;
Inert atmosphere;
|
|
|
In
dichloromethane;
at 20 ℃;
|
|
|
at 0 - 25 ℃;
|
|
|
at 50 - 60 ℃;
for 2h;
|
292 g
|
|
at 0 - 25 ℃;
|
|
|
In
dichloromethane;
at 0 ℃;
|
|
|
In
dichloromethane;
at 0 - 20 ℃;
|
|
|
In
dichloromethane;
at 0 - 25 ℃;
|
2.What is the CAS number for 3-Fluoroacetanilide ?
The CAS number of 3-Fluoroacetanilide is 351-28-0.
More information of 3-Fluoroacetanilide 351-28-0 are:
|
CAS?Number |
351-28-0 |
|
Density |
1.209 g/cm3 |
|
Melting Point |
82-84 °C(lit.) |
|
Boiling Point |
293.334 °C at 760 mmHg |
|
Flash Point |
131.204 °C |
|
Vapor Pressure |
0.00174mmHg at 25°C |
|
Refractive Index |
1.552 |
|
HS CODE |
29242990 |
|
PSA |
29.10000 |
|
LogP |
1.85710 |
|
Pka |
14.34±0.70(Predicted) |
3.What are another words for 3-Fluoroacetanilide ?
Synonyms?for?3-Fluoroacetanilide 351-28-0:Acetanilide,3'-fluoro- (6CI,7CI,8CI);N-(3-Fluorophenyl)acetamide;N-Acetyl-3-fluoroaniline;N-Methylcarbonyl-3-fluoroaniline;NSC 10348;m-Fluoroacetanilide;
4.What is the molecular formula of 3-Fluoroacetanilide?
The chemical formula of ?3-Fluoroacetanilide is?C8H8FNO which containing 8 Carbon atoms,8 Hydrogen atoms,1 Fluorine atoms,1 Nitrogen atoms and 1 Oxygen atoms,and the molecular weight of??3-Fluoroacetanilide?is 153.156.
5.What is 3-Fluoroacetanilide (351-28-0) used for?
3-Fluoroacetanilide is an off-white crystalline powder that serves as a key reactant in the synthesis of various chemical compounds, particularly in the preparation of trifluoromethylaryl acetamides.
InChI:InChI=1/C8H8FNO/c1-6(11)10-8-4-2-3-7(9)5-8/h2-5H,1H3,(H,10,11)
Relevant articles related to 3-Fluoroacetanilide:
|
Article |
Source |
|
Z-Selective Fluoroalkenylation of (Hetero)Aromatic Systems by Iodonium Reagents in Palladium-Catalyzed Directed C?H Activation |
Bényei, Attila,Domján, Attila,Egyed, Orsolya,Gonda, Zsombor,Novák, Zoltán,Sályi, Gerg?,Tóth, Balázs L. supporting information, (2021/11/09) |
|
Method for promoting acylation of amine or alcohol by carbon dioxide |
- Paragraph 0033-0034, (2021/05/29) |
6.Buy 3-Fluoroacetanilide with the best price .
Shanghai Anya Chemicals Co.,Ltd is a quality supplier of 3-Fluoroacetanilide. Our main goal is customer satisfaction. Contact us to negotiate the best price for your business on 3-Fluoroacetanilide 351-28-0.
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