3-Fluoroacetanilide

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1.What is the 3-Fluoroacetanilide ?

3''-Fluoroacetanilide is a reactant in the preparation of trifluoromethylaryl acetamides via Pd-catalyzed trifluoromethylation of aromatics C-H bond with Umemoto''s reagent directed by acetamino group.

meta-fluoroaniline
372-19-0

meta-fluoroaniline

acetonitrile
75-05-8,26809-02-9

acetonitrile

N-(3-fluorophenyl)acetamide
351-28-0

N-(3-fluorophenyl)acetamide

Conditions
Conditions Yield
With aluminum oxide; at 200 ℃; for 0.45h; under 37503.8 Torr; Sonication; Green chemistry;
99%
With chloro-trimethyl-silane; potassium iodide; at 110 ℃; for 0.25h; Microwave irradiation;
76%
With tert.-butylnitrite; trifluorormethanesulfonic acid; water; at 60 ℃; for 24h;
45%
meta-fluoroaniline
372-19-0

meta-fluoroaniline

acetic anhydride
108-24-7

acetic anhydride

N-(3-fluorophenyl)acetamide
351-28-0

N-(3-fluorophenyl)acetamide

Conditions
Conditions Yield
With acetic acid; at 105 ℃; for 3h;
100%
With silica-coated ferrite nanoparticles supported with montmorillonite-K10; at 20 ℃; for 0.333333h;
92%
With sodium acetate; In water; at 0 ℃; for 1h; Inert atmosphere;
87%
at 0 - 20 ℃; Inert atmosphere;
84%
at 50 ℃; for 3h;
82%
at 0 - 70 ℃; Inert atmosphere;
71%
In acetic acid; for 0.333333h; Heating;
70%
With acetic acid;
70%
With benzene;
In dichloromethane; at 20 ℃; Inert atmosphere;
With sodium dodecyl sulfate; In water; at 20 ℃; for 0.5h;
In dichloromethane; at 20 ℃; Inert atmosphere;
In dichloromethane; at 20 ℃;
at 0 - 25 ℃;
at 50 - 60 ℃; for 2h;
292 g
at 0 - 25 ℃;
In dichloromethane; at 0 ℃;
In dichloromethane; at 0 - 20 ℃;
In dichloromethane; at 0 - 25 ℃;

2.What is the CAS number for 3-Fluoroacetanilide ?

The CAS number of 3-Fluoroacetanilide is 351-28-0.

More information of 3-Fluoroacetanilide 351-28-0 are:

CAS?Number

351-28-0

Density

1.209 g/cm3

Melting Point

82-84 °C(lit.)

Boiling Point

293.334 °C at 760 mmHg

Flash Point

131.204 °C

Vapor Pressure

0.00174mmHg at 25°C

Refractive Index

1.552

HS CODE

29242990

PSA

29.10000

LogP

1.85710

Pka

14.34±0.70(Predicted)

3.What are another words for 3-Fluoroacetanilide ?

Synonyms?for?3-Fluoroacetanilide 351-28-0:Acetanilide,3'-fluoro- (6CI,7CI,8CI);N-(3-Fluorophenyl)acetamide;N-Acetyl-3-fluoroaniline;N-Methylcarbonyl-3-fluoroaniline;NSC 10348;m-Fluoroacetanilide;

4.What is the molecular formula of 3-Fluoroacetanilide?

The chemical formula of ?3-Fluoroacetanilide is?C8H8FNO which containing 8 Carbon atoms,8 Hydrogen atoms,1 Fluorine atoms,1 Nitrogen atoms and 1 Oxygen atoms,and the molecular weight of??3-Fluoroacetanilide?is 153.156.

5.What is 3-Fluoroacetanilide (351-28-0) used for?

3-Fluoroacetanilide is an off-white crystalline powder that serves as a key reactant in the synthesis of various chemical compounds, particularly in the preparation of trifluoromethylaryl acetamides.

InChI:InChI=1/C8H8FNO/c1-6(11)10-8-4-2-3-7(9)5-8/h2-5H,1H3,(H,10,11)

Relevant articles related to 3-Fluoroacetanilide:

Article

Source

Z-Selective Fluoroalkenylation of (Hetero)Aromatic Systems by Iodonium Reagents in Palladium-Catalyzed Directed C?H Activation

Bényei, Attila,Domján, Attila,Egyed, Orsolya,Gonda, Zsombor,Novák, Zoltán,Sályi, Gerg?,Tóth, Balázs L.

supporting information, (2021/11/09)

Method for promoting acylation of amine or alcohol by carbon dioxide

-

Paragraph 0033-0034, (2021/05/29)

6.Buy 3-Fluoroacetanilide with the best price .

Shanghai Anya Chemicals Co.,Ltd is a quality supplier of 3-Fluoroacetanilide. Our main goal is customer satisfaction. Contact us to negotiate the best price for your business on 3-Fluoroacetanilide 351-28-0.

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